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A young physician named John Gorrie moved to Apalachicola in the early 1800s when it was a prominent port of trade, commerce, and shipping in Florida. Gorrie served as postmaster, city treasurer, town councilman, and bank director. Concern for his yellow fever patients motivated Gorrie to invent a method for cooling their rooms. He became a pioneer in the field of air conditioning and refrigeration by inventing a machine that made ice, and received the first U.S. Patent for mechanical refrigeration in 1851. A replica of his ice-making machine is on display at the museum, as well as exhibits chronicling the colorful history of Apalachicola, which played an important role in Florida's economic development.